Patient‐Derived IgG Epitope Mapping of Bet v 1 Reveals Hypoallergenic Peptide Candidates for Safe and Next‐Generation Allergen Immunotherapy

Key Points

• The research aims to identify peptides that elicit protective IgG responses for improved allergen therapy.
• Used patient-derived samples for epitope mapping
• Identified peptides that selectively engage IgG responses
• Developed a framework for allergen immunotherapy
• Identified multiple hypoallergenic peptides
• Peptides showed selective IgG engagement
• Suggested potential for next-generation allergen immunotherapy