What question did this study set out to answer?

To examine the association between high body-mass index (BMI) and the risk of multiple myeloma (MM), identifying potential treatment targets.

March 13, 2026Open Access

High body-mass index and multiple myeloma risk: insights from the global burden of disease 2021 study and identification of core target genes

Key Points

To examine the association between high body-mass index (BMI) and the risk of multiple myeloma (MM), identifying potential treatment targets.
Analysis of data from the Global Burden of Disease 2021 study.
Identification of key genes associated with high BMI and multiple myeloma.
Review of public health implications related to high BMI.
High BMI is associated with an increased risk of multiple myeloma.
SLC25A13 and THOC2 identified as potential treatment targets for high BMI-associated MM.
Findings emphasize the need for targeted public health interventions.

Abstract

The above findings underscore the growing public health threat posed by high BMI-associated MM and highlight the need for targeted interventions. SLC25A13 and THOC2 may play an important role in high BMI-associated MM and could serve as potential treatment targets in the future.

High body-mass index and multiple myeloma risk: insights from the global burden of disease 2021 study and identification of core target genes

Key Points

Abstract

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