Intraoperative monitoring revealed distinct patterns in nociceptive dynamics and their coupling with anesthetic depth between OFA and OBA techniques. OBA showed a tighter coupling between nociception and anesthetic depth, whereas both approaches appeared suboptimal for postoperative pain control. Despite these intraoperative variations, the overall impact on early postoperative recovery was limited. Larger, prospective studies are warranted to assess how nociception-guided anesthesia strategies and time within specific NOL intervals influence postoperative pain and long-term outcomes.
Norbeck et al. (Thu,) studied this question.