Comparing procalcitonin and C-reactive protein levels in very low birth weight infants with sepsis

Key Points

• The aim is to compare the sensitivity and specificity of procalcitonin and C-reactive protein in identifying sepsis in very low birth weight infants.
• Analyzed levels of procalcitonin and C-reactive protein in very low birth weight infants.
• Used multivariable models to identify independent predictors of sepsis.
• Compiling data from one of the largest cohorts in the U.S.
• Procalcitonin shows higher sensitivity for sepsis but lower specificity compared to C-reactive protein.
• C-reactive protein is identified as a stronger independent predictor of sepsis.
• Findings suggest the relevance of CRP in clinical settings for high-risk infants.