ABSTRACT Lymphangioma is a congenital malformation of the lymphatic system, commonly affecting the head and neck region. Macroglossia due to lymphangioma in adolescence is uncommon, making this case noteworthy. This condition can affect oral function, speech, and quality of life, making early diagnosis and intervention essential. This report highlights a 14‐year‐old Balouch female presenting with progressive tongue enlargement beginning at age five. Intraoral examination revealed an enlarged tongue with a pebbly surface, particularly involving the ventral side of the tongue, without osseous involvement on radiographs. Differential diagnoses included hemangioma and lymphangiomegaly; however, histopathological analysis confirmed lymphangioma. The patient underwent sclerotherapy, resulting in a significant reduction in tongue size, improved oral function, and resolution of related symptoms. Follow‐up revealed no recurrence or major complications. Early recognition and appropriate management of lymphangioma‐induced macroglossia are essential to prevent functional limitations and improve quality of life. While surgical excision remains the conventional treatment, sclerotherapy offers a less invasive, effective alternative with lower morbidity. This case contributes to the limited literature on adolescent‐onset oral lymphangioma and underscores the value of a multidisciplinary approach in ensuring optimal outcomes.
Heidary et al. (Sun,) studied this question.