What question did this study set out to answer?

The aim is to explore how laterality affects inpatient outcomes and complications in acute ischemic stroke patients.

March 15, 2026

Impact of Laterality on Inpatient Outcomes and Complications of Middle Cerebral Artery Acute Ischemic Stroke

SAS. AlbertAnna Needs Neuroblastoma Answers AJAarti Kishore JainWestchester Medical Center AMAryan MalhotraBurdwan Medical College & Hospital

Key Points

The aim is to explore how laterality affects inpatient outcomes and complications in acute ischemic stroke patients.
Observational study of inpatient outcomes in patients with acute ischemic stroke.
Comparison of outcomes based on laterality of Middle Cerebral Artery Stroke.
Assessment of treatment differences including thrombectomy and thrombolysis.
Patients with right MCAS had worse discharge disposition.
Increased likelihood of inpatient mortality in right MCAS patients.
Recognition of nondominant hemisphere strokes may improve treatment and outcomes.

Abstract

Patients with R-MCAS were more likely to receive endovascular thrombectomy and less likely to receive intravascular thrombolysis. R-MCASs were also associated with worse discharge disposition and increased likelihood of inpatient mortality. The National Institutes of Health Stroke Scale bias toward assessment and valuation of patients' language abilities may place patients with R-MCAS at increased risk of adverse poststroke outcomes and complications. Recognition of the subtle signs of nondominant hemisphere strokes may lead to more rapid detection, effective treatment, and improved outcomes.

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