Amyloid β-related angiitis (ABRA) with dural contrast enhancement

Key Points

• To investigate a case of cognitive decline associated with Amyloid β-related angiitis (ABRA) and its treatment.
• Conducted a brain biopsy for diagnosis after observing atypical dural contrast enhancement.
• Utilized head MRI to assess brain pathology related to cognitive symptoms.
• Monitored response to steroid therapy in managing symptoms and imaging findings.
• Identified ABRA through brain biopsy despite atypical imaging features.
• Observed significant improvement in cognitive function and imaging characteristics post-steroid therapy.
• Noted inflammation in the leptomeninges extending towards brain tissue and dura.