Relationship between Clostridioides Difficile Infections and Antimicrobial Use in Patients with Hematopoietic Diseases
Key Points
To investigate how continued use of broad-spectrum antibiotics affects the outcomes of Clostridioides difficile infection in patients with hematopoietic diseases.
Analyzed data on CDI in patients with hematopoietic diseases
Assessed impact of broad-spectrum antibiotic usage on treatment outcomes
Evaluated cure and relapse rates
Continued antibiotic use correlated with higher relapse rates of CDI
Broader spectrum antibiotics did not significantly improve cure rates
Findings suggest careful management of antibiotic use is necessary for affected patients
Abstract
Objective To clarify the impact of the continued use of broad-spectrum antibiotics on the cure and relapse rates of Clostridioides difficile infection (CDI) in patients with hematopoietic diseases.