A Rapid Chemiluminescence Immunoassay for Plasmin-α2 antiplasmin Complex Utilizing Novel Monoclonal Antibodies

Key Points

• The research focuses on creating specific monoclonal antibodies for detecting plasmin-α2-antiplasmin complex.
• Developed monoclonal antibodies targeting plasmin-α2-antiplasmin complex.
• Utilized a chemiluminescence immunoassay for rapid detection.
• Validated the specificity and sensitivity of the antibodies.
• Demonstrated high specificity of the monoclonal antibodies for the plasmin-α2-antiplasmin complex.
• Achieved rapid detection capabilities for fibrinolytic activation.
• Identified the plasmin-α2-antiplasmin complex as an early biomarker.