Alternative splicing in voltage-gated sodium channels is a central pathophysiological mechanism that provides an emerging target for precision medicine therapies in VGSC-associated disorders.
Absolute Event Rate: 0% vs 0%
By integrating mechanistic insights with clinical implications, this review establishes alternative splicing as a central theme in VGSC biology and pathophysiology. It highlights the critical need for, and the emerging path towards, precision medicine approaches that target splicing defects for the treatment of VGSC-associated disorders, providing a foundational resource to guide future research and therapeutic development.
Qiu et al. (Mon,) reported a other. Alternative splicing in voltage-gated sodium channels is a central pathophysiological mechanism that provides an emerging target for precision medicine therapies in VGSC-associated disorders.