Alpha‐synuclein co‐pathology in a real‐world early Alzheimer's disease cohort
Key Points
To investigate the relationship between αS-SAA positivity and olfactory dysfunction in early Alzheimer's disease.
Analyzed αS-SAA positivity in an early Alzheimer's disease cohort.
Conducted longitudinal follow-up to assess symptom progression and potential treatment response.
Evaluated olfactory function in patients diagnosed with early Alzheimer's.
αS-SAA positivity was found to be common in the early stages of Alzheimer's disease.
A significant association was observed between αS-SAA positivity and olfactory dysfunction.
Further longitudinal studies are needed to determine if assay status can predict treatment responses.
Abstract
αS-SAA positivity is common in early AD and associated with olfactory dysfunction. Longitudinal follow-up is required to test if assay status predicts response to ATTs.