Introduction: Japan's diabetic nephropathy prevention initiatives have successfully reduced dialysis initiation, but aging populations now face rising non-diabetic chronic kidney disease (CKD), particularly nephrosclerosis.National health policy has shifted toward non-diabetic CKD prevention, yet municipal implementation remains inconsistent.Current uniform screening approaches achieve only 3% disease awareness and 10% consultation rates among Japanese CKD patients.We established an industry-university-government collaboration to develop and evaluate a comprehensive non-diabetic CKD screening system, creating a scalable municipal implementation model.Methods: We developed a multi-stakeholder framework involving Ichinomiya City, Nagoya University, and PREVENT Inc. to create personalized screening interventions for non-diabetic CKD patients.The study employs a two-phase approach: (1) prototype development using PREVENT's 1-million-person corporate health insurance database to identify healthcare utilization patterns through claims data analysis, and (2) regional implementation using Ichinomiya City's national health insurance and health checkup data.Our approach combines claims-derived healthcare behavior clustering with nudge theory-based individualized notification systems, integrated with faceto-face consultation guidance at community pharmacies and multiprofessional care coordination.Target population focuses specifically on non-diabetic CKD patients with poor blood pressure control, enabling precise intervention development for this emerging high-risk population.Results: The target municipality encompasses approximately 60,000 national health insurance enrollees, with approximately 630 non-diabetic CKD patients showing poor blood pressure control identified among 2024 health screening participants.PREVENT preliminary analysis revealed distinct healthcare utilization patterns among nondiabetic CKD patients, where consultation frequency, care continuity, and comorbidity management behaviors were associated with subsequent CKD diagnosis coding and biochemical testing implementation in the following year.Comprehensive outcome indicators were established, encompassing consultation rates, CKD diagnostic codes, laboratory testing implementation, and chronic kidney disease prevention guidance fees in collaboration with municipal data infrastructure.Implementation framework was successfully established, including community pharmacy networks and multi-professional collaboration systems at regional core hospitals.Conclusion: This project establishes the foundation for developing an evidence-based personalized screening system targeting non-diabetic CKD patients, addressing Japan's evolving national policy priorities.The preliminary identification of healthcare utilization patterns provides the ground work for developing precision interventions.Our municipality-university-industry collaboration framework provides a replicable framework for nationwide implementation, directly supporting national CKD prevention policy advancement.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.
Oki et al. (Wed,) studied this question.