What question did this study set out to answer?

To investigate the impact of COVID-19 infection during pregnancy on obstetric and neonatal outcomes.

March 28, 2026Open Access

The Effect of COVID ‐19 During Pregnancy on Obstetric and Neonatal Outcomes: A Retrospective Case–Control Study

LMLaura McDuffThe University of Notre Dame Australia PBPatricia de Gouveia BelineloThe University of Notre Dame Australia SLSimon K. LawranceThe University of Western Australia

Key Points

To investigate the impact of COVID-19 infection during pregnancy on obstetric and neonatal outcomes.
Retrospective case-control design
Comparison of pregnant individuals with and without COVID-19
Assessment of obstetric and neonatal outcomes
COVID-19 infection was not linked to significant adverse outcomes
Influence of the Omicron strain and high vaccination rates noted
Study limitations included lack of universal screening and small sample size

Abstract

COVID-19 infection during pregnancy was not associated with clinically significant adverse outcomes, likely influenced by the predominant Omicron strain and high vaccination rates. Limitations of this study included lack of universal screening and a small sample size. Notwithstanding, this study provides valuable insights that reflect the current COVID-19 landscape, underscoring the need for an updated understanding as context surrounding COVID-19 infection evolves.

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