What question did this study set out to answer?

To evaluate the effectiveness of ceftazidime-avibactam as a salvage therapy for serious infections in critically ill pediatric patients.

March 29, 2026European Journal of Pediatrics0 citationsOpen Access

Ceftazidime–avibactam for multidrug and pandrug-resistant gram-negative infections in critically Ill children: a single-center pediatric ıntensive care experience

MHMerve HavanAnkara University GAGül ArgaAnkara University YBYunus Emre BulbulAnkara University

Key Points

To evaluate the effectiveness of ceftazidime-avibactam as a salvage therapy for serious infections in critically ill pediatric patients.
Used ceftazidime-avibactam as treatment for multidrug- and pandrug-resistant infections.
Conducted in a pediatric intensive care unit (PICU).
Monitored clinical and microbiological responses.
High clinical response rates were noted among critically ill children.
Microbiological improvement was observed despite prior extensive antibiotic use.

Abstract

• Ceftazidime-avibactam was used as salvage therapy for multidrug- and pandrug-resistant Gram-negative infections in critically ill children. • Clinical and microbiological response was achieved in a high-risk PICU population despite prolonged hospitalization and extensive prior antibiotic exposure.

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