Targeting and self-assembling peptides mimic fibrinogen coagulation for alleviating hypofibrinogenemia

Key Points

• The aim is to explore a new treatment for fibrinogen deficiency-related bleeding disorders using self-assembling peptides.
• Investigated self-assembling peptides designed to mimic fibrinogen
• Tested the efficacy of these peptides in coagulation processes
• Examined potential for clinical application in treating hypofibrinogenemia
• Peptides effectively mimicked fibrinogen's coagulation properties
• Demonstrated potential to alleviate symptoms associated with hypofibrinogenemia
• Indicated a promising alternative to blood-derived products