Does culprit-lesion-only PCI reduce the risk of death or renal-replacement therapy compared to immediate multivessel PCI in patients with acute myocardial infarction and cardiogenic shock?
In patients with AMI and cardiogenic shock, culprit-lesion-only PCI reduces the 30-day risk of death or renal replacement therapy compared to immediate multivessel PCI, though 1-year mortality does not differ significantly.
Among patients with acute myocardial infarction and cardiogenic shock, the risk of death or renal-replacement therapy at 30 days was lower with culprit-lesion-only PCI than with immediate multivessel PCI, and mortality did not differ significantly between the two groups at 1 year of follow-up. (Funded by the European Union Seventh Framework Program and others; CULPRIT-SHOCK ClinicalTrials.gov number, NCT01927549 .).
Thiele et al. (Sat,) studied this question.