Chikungunya virus infection caused rhabdomyolysis in three elderly men with comorbidities, presenting with creatine phosphokinase levels ranging from 1105 to 46810 U/L.
Chikungunya virus infection can cause severe rhabdomyolysis in elderly patients with comorbidities, necessitating prompt recognition and fluid management.
Absolute Event Rate: 0% vs 0%
Abstract Background Chikungunya virus (CHIKV) is an arbovirus causing febrile illness with musculoskeletal symptoms. Although self-limiting, Chikungunya can result in rhabdomyolysis, with the risk of acute kidney injury. Methods We report three elderly men with comorbidities who developed rhabdomyolysis during the 2025 outbreak. Results Clinical features included fever, myalgia, confusion, quadriplegia and muscle oedema; creatine phosphokinase (CPK) ranged from 1105 to 46810 U/L. RT-PCR confirmed CHIKV in two cases. All were managed with intravenous fluids and renal and electrolyte monitoring, with variable recovery. Conclusions Rhabdomyolysis is under-recognized; clinicians should maintain high suspicion in older patients with comorbidities, monitor CPK and treat promptly.
Silva et al. (Thu,) reported a other. Chikungunya virus infection caused rhabdomyolysis in three elderly men with comorbidities, presenting with creatine phosphokinase levels ranging from 1105 to 46810 U/L.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: