Base-free reduction of ketones using a bpy-iridium catalyst. Focus on the synthesis of γ-valerolactone

Key Points

• The aim is to explore the base-free reduction of ketones utilizing a bpy-iridium catalyst to synthesize γ-valerolactone.
• Preparation of various [Cp*Ir(N⌒N)SO4] complexes.
• Evaluation of catalyst efficiency for ketone reduction in water.
• Use of formic acid as a hydrogen donor without additives.
• The catalysts showed efficient reduction of multiple ketones.
• A specific catalyst displayed optimal performance for γ-valerolactone synthesis.
• Reduction occurred effectively in an aqueous environment.