Crohn’s disease can adversely affect bone mineral density and low bone mineral density is a concern in pediatric Crohn’s disease. We evaluated factors associated with below-average bone mineral density (z-score ≤ − 1.0) at Crohn’s disease diagnosis. We retrospectively analyzed patients − 1.0, children with z–score ≤ − 1.0 were more often female, had lower hematocrit and weight/height/body mass index z-scores, higher Pediatric Crohn’s Disease Activity Index at diagnosis, and more frequent growth delay (all P < 0.05). Lower weight z-score (OR 0.465, P < 0.001) and growth delay (OR 1.846, P 0.011) were independently associated with below-average bone mineral density. Lower weight z-score and growth delay are independently linked to below-average bone mineral density at Crohn’s disease diagnosis. These findings highlight the importance of evaluating bone mineral density at diagnosis and closely monitoring patients with these risk factors.
Kim et al. (Thu,) studied this question.