Impact of hypoglycemic agents on glycemic control and cognitive decline in older adults with type 2 diabetes: real-world evidence on glucagon like peptide 1 receptor agonists

Key Points

• To investigate the effects of hypoglycemic agents on glycemic control and cognitive decline in older adults with type 2 diabetes.
• Evaluated real-world data on older adults with type 2 diabetes
• Examined the effects of different drug classes on glycemic control
• Measured HbA1c levels
• Assessed cognitive function using the MMSE scale
• GLP-1 receptor agonists (GLP-1RAs) showed the largest reductions in HbA1c levels
• Linked greater improvements in cognitive scores (MMSE) to better glycemic control