Granular Cell Tumour (GCT) is a rare and painless benign soft tissue neoplasm of Schwann cell derivative. It is a slow-growing, firm, and solitary nodule usually smaller than 3 cm in diameter that frequently occurs in females between 4th-6th decade of life. We aim to describe the clinical presentation of the granular cell tumour (GCT) and the histopathological tools used to achieve its definitive diagnosis.We present a case of GCT of the tongue in a 46-year old female who presented with a year-old painless swelling on the tongue in our dental clinic. There was associated tenderness but disturbed deglutition. Clinical examination revealed a firm swelling in the right anterior two-thirds. Differential diagnoses made were chondroma, fibroma, and rhabdomyoma. Excisional biopsy for histopathological and immunohistochemical evaluation was diagnostic of GCT.GCT may be confused with other oral lesions clinically, but the use of histopathological and immunohistochemical tools confirmed its diagnosis.
Castano et al. (Fri,) studied this question.