Does colchicine 0.5 mg daily reduce ischemic cardiovascular events in patients with a recent myocardial infarction?
Low-dose colchicine (0.5 mg daily) significantly reduces the risk of ischemic cardiovascular events following a recent myocardial infarction.
Among patients with a recent myocardial infarction, colchicine at a dose of 0.5 mg daily led to a significantly lower risk of ischemic cardiovascular events than placebo. (Funded by the Government of Quebec and others; COLCOT ClinicalTrials.gov number, NCT02551094.).
“In addition to standard of care in patients with a recent MI, colchicine 0.5 mg daily significantly reduces the risk for first ischemic CV events by 23% and total ischemic cardiovascular events by 34%.”
Tardif et al. (Sat,) studied this question.