April 16, 2020Open Access

Prevalence of Antibiotic-Resistant Pathogens in Culture-Proven Sepsis and Outcomes Associated With Inadequate and Broad-Spectrum Empiric Antibiotic Use

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Abstract

IMPORTANCE Broad-spectrum antibiotics are recommended for all patients with suspected sepsis to minimize the risk of undertreatment. However, little is known regarding the net prevalence of antibiotic-resistant pathogens across all patients with community-onset sepsis or the outcomes associated with unnecessarily broad empiric treatment.

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Rhee et al. (Thu,) studied this question.

synapsesocial.com/papers/69d56c4d75589c71d767cd57 https://doi.org/https://doi.org/10.1001/jamanetworkopen.2020.2899

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