Does cardiometabolic multimorbidity increase mortality risk compared to single conditions?
Having multiple cardiometabolic conditions (diabetes, stroke, MI) confers a multiplicative mortality risk, significantly reducing life expectancy.
Mortality associated with a history of diabetes, stroke, or MI was similar for each condition. Because any combination of these conditions was associated with multiplicative mortality risk, life expectancy was substantially lower in people with multimorbidity.
Angelantonio et al. (Tue,) studied this question.