Does tailored atrial substrate modification based on low-voltage areas in addition to circumferential pulmonary vein isolation improve 12-month outcomes in patients with atrial fibrillation?
A tailored voltage-based approach for substrate modification alongside pulmonary vein isolation may improve outcomes for AF patients with endocardial structural defects.
LVAs can be found at preferred sites in 10% of patients with paroxysmal AF and in 35% of patients with persistent AF. This is the first clinical report describing a consistent voltage-based approach for substrate modification in addition to circumferential pulmonary vein isolation irrespective of AF type. Application of this limited individualized approach may have the potential to compensate for the impaired 12-month outcome of patients with endocardial structural defects.
Rolf et al. (Sun,) studied this question.