Identifies unique obesity-inflammation phenotypes in HFpEF that correlate with disease severity and fibrosis, supporting comorbidity-driven microvascular inflammation as a key mechanism.
Unique obesity-inflammation phenotypes exist in HFpEF and are associated with differences in comorbidity burden, HFpEF severity, and fibrosis. These data support comorbidity-driven microvascular inflammation as a pathophysiologic mechanism for many but not all HFpEF patients.
Sabbah et al. (Wed,) studied this question.
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