The Clinical Practice Research Datalink (CPRD) in the UK is a valid data source for identifying cardiovascular outcomes like AMI and stroke, as well as key risk factors.
AMI, stroke, smoking, obesity, and postmenopausal status can be accurately identified in CPRD. Physician questionnaire-validated AMI and stroke cases yield IRRs closest to the best estimate.
Arana et al. (Fri,) studied this question.