Does the anti-Factor Xa assay correlate better with heparin dose than activated partial thromboplastin time or activated clotting time in pediatric extracorporeal membrane oxygenation?
In pediatric extracorporeal membrane oxygenation, the anti-Factor Xa assay is a more valuable monitor of heparin administration than ACT or aPTT due to its superior correlation with heparin dosing.
The anti-Factor Xa assay correlated better with heparin dosing than activated clotting time or activated partial thromboplastin time. Activated clotting time has a poor correlation to heparin doses commonly associated with extracorporeal membrane oxygenation. In pediatric extracorporeal membrane oxygenation, anti-Factor Xa assay may be a more valuable monitor of heparin administration.
Liveris et al. (Thu,) studied this question.