Does physiology-guided complete revascularization reduce the composite risk of death, myocardial infarction, stroke, or ischemia-driven revascularization at 1 year in patients 75 years of age or older with myocardial infarction and multivessel disease compared to culprit-lesion-only PCI?
Physiology-guided complete revascularization improves 1-year clinical outcomes compared to culprit-only PCI in older patients (≥75 years) presenting with myocardial infarction and multivessel disease.
Among patients who were 75 years of age or older with myocardial infarction and multivessel disease, those who underwent physiology-guided complete revascularization had a lower risk of a composite of death, myocardial infarction, stroke, or ischemia-driven revascularization at 1 year than those who received culprit-lesion-only PCI. (Funded by Consorzio Futuro in Ricerca and others; FIRE ClinicalTrials.gov number, NCT03772743.).
Biscaglia et al. (Sat,) studied this question.