January 1, 2012Open Access

Evidence for Astrocytosis in Prodromal Alzheimer Disease Provided by 11 C-Deuterium-L-Deprenyl: A Multitracer PET Paradigm Combining 11 C-Pittsburgh Compound B and 18 F-FDG

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Abstract

Increased (11)C-DED binding throughout the brain of the MCI (11)C-PIB+ patients potentially suggests that astrocytosis is an early phenomenon in AD development.

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Carter et al. (Sun,) studied this question.

synapsesocial.com/papers/69d6cecf41375cf86eed8c2d https://doi.org/https://doi.org/10.2967/jnumed.110.087031

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