January 25, 2016Hepatology142 citationsOpen Access

Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice

YLYuanyuan LiHebei Medical University MZMunaf H. ZalzalaUniversity of Baghdad KJKavita JadhavUniversity of Kansas

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Abstract

CES2 plays a protective role in development of NAFLD. Targeting the HNF-4α/CES2 pathway may be useful for treatment of NAFLD. (Hepatology 2016;63:1860-1874).

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Li et al. (Mon,) studied this question.

synapsesocial.com/papers/69d70e55f174babf6cab3e77 https://doi.org/https://doi.org/10.1002/hep.28472

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