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Advances in the pathophysiology of primary immune thrombocytopenia | Synapse

September 27, 2016Open Access

Advances in the pathophysiology of primary immune thrombocytopenia

Key Points

Key points are not available for this paper at this time.

Abstract

A better understanding of the immunomodulatory effects of each ITP therapy is needed to best manage the disease.

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Perera et al. (Tue,) studied this question.

synapsesocial.com/papers/69d71cbe8a0e2c5879bef2a8 https://doi.org/https://doi.org/10.1080/10245332.2016.1219497

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Immune Dysregulation in Immune Thrombocytopenia2013 · 50 citations
2Mechanisms of thrombocytopenia in chronic autoimmune thrombocytopenic purpura. Evidence of both impaired platelet production and increased platelet clearance.1987 · 401 citations
3Immune Thrombocytopenia: Pathophysiologic and Clinical Update2012 · 96 citations
4Incomplete antigenic cross-reactivity between platelets and megakaryocytes: relevance to ITP1986 · 50 citations
5Presence of cross-reactive antibody between human immunodeficiency virus (HIV) and platelet glycoproteins in HIV-related immune thrombocytopenic purpura1992 · 106 citations