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Kohany et al. (Wed,) studied this question.
synapsesocial.com/papers/69d71e97ef370a38abf50a88 — DOI: https://doi.org/10.1186/1471-2105-7-474
Oleksiy Kohany
Genetic Information Research Institute
Andrew J. Gentles
Stanford University
Lukasz Hankus
Genetic Information Research Institute
SHILAP Revista de lepidopterología
BMC Bioinformatics
Stanford University
Genetic Information Research Institute
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