July 28, 2023Open Access

Identification of drug resistance in a validated cohort of incident epilepsy patients in the Danish National Patient Register

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Abstract

In the DNPR, we found a PPV of the epilepsy diagnosis of 79%. Among persons with confirmed epilepsy, 14% fulfilled ILAE criteria for DRE. Early age at epilepsy onset, cognitive impairment, and a history of status epilepticus were independently associated with drug resistance.

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Bølling‐Ladegaard et al. (Fri,) studied this question.

synapsesocial.com/papers/69d76490aa68b335b4f3130e https://doi.org/https://doi.org/10.1111/epi.17732

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1ILAE Official Report: A practical clinical definition of epilepsy2014 · 5,946 citations
2Cause‐Specific Mortality in Epilepsy: A Cohort Study of More Than 9,000 Patients Once Hospitalized for Epilepsy1997 · 327 citations
3Poor versus rich children with epilepsy have the same clinical course and remission rates but a less favorable social outcome: A population‐based study with 25 years of follow‐up2016 · 33 citations
4Early predictors of medical intractability in childhood epilepsy2003 · 91 citations
5Intrinsic Severity as a Determinant of Antiepileptic Drug Refractoriness2008 · 164 citations

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