December 22, 2009Open Access

Brain Volume and Metabolism in Fetuses With Congenital Heart Disease

CLCatherine LimperopoulosGeorge Washington University Hospital WTWayne TworetzkyPediatric Cardiology

Doff B. McElhinneyPediatric / Congenital Cardiology

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Abstract

Third-trimester fetuses with some forms of CHD have smaller gestational age- and weight-adjusted total brain volumes than normal fetuses and evidence of impaired neuroaxonal development and metabolism. Hemodynamic factors may play an important role in this abnormal development.

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Limperopoulos et al. (Tue,) studied this question.

synapsesocial.com/papers/69d79fa4f44a16d01ef31b76 https://doi.org/https://doi.org/10.1161/circulationaha.109.865568

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