December 2, 2005

A Predominantly Clonal Multi-Institutional Outbreak ofClostridium difficile–Associated Diarrhea with High Morbidity and Mortality

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Abstract

A strain of C. difficile that was resistant to fluoroquinolones and had binary toxin and a partial deletion of the tcdC gene was responsible for this outbreak of C. difficile-associated diarrhea. Exposure to fluoroquinolones or cephalosporins was a risk factor.

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Loo et al. (Fri,) studied this question.

synapsesocial.com/papers/69d7c842e57cdc1cc9ae2d0b https://doi.org/https://doi.org/10.1056/nejmoa051639

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Clostridium difficile colitis: An increasing hospital-acquired illness1995 · 182 citations
2The pathogenicity of Clostridium difficile2001 · 156 citations
3The Importance of Severity of Illness in Assessing Hospital Mortality1990 · 219 citations
4Risk factors for Clostridium difficile carriage and C. difficile-associated diarrhea in a cohort of hospitalized patients1992 · 363 citations
5Fulminant Clostridium difficile: An Underappreciated and Increasing Cause of Death and Complications2002 · 626 citations

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