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Both C4d deposition in lesional skin and elevated C5a levels in peripheral blood indicate the involvement of complement activation in the pathogenesis of CSU. No correlation was found between omalizumab and activation of complement indicative of independent processes in the immunopathogenesis of CSU.
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Aghdam et al. (Thu,) studied this question.
synapsesocial.com/papers/69d7d01fa2a48916bbbedcb3 — DOI: https://doi.org/10.1002/clt2.12011
Mehran Alizadeh Aghdam
Utrecht University
Mignon van den Elzen
Utrecht University
Harmieke van Os‐Medendorp
Saxion
SHILAP Revista de lepidopterología
Clinical and Translational Allergy
Utrecht University
University Medical Center Utrecht
University of Applied Sciences Utrecht
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