April 4, 2016Open Access

Increased Reactive Oxygen Species Formation and Oxidative Stress in Rheumatoid Arthritis

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Abstract

RA patients showed a marked increase in ROS formation, lipid peroxidation, protein oxidation, DNA damage and decrease in the activity of antioxidant defence system leading to oxidative stress which may contribute to tissue damage and hence to the chronicity of the disease.

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Mateen et al. (Mon,) studied this question.

synapsesocial.com/papers/69d7f83b11d83f35e5ae37b3 https://doi.org/https://doi.org/10.1371/journal.pone.0152925

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1[30] Microsomal lipid peroxidation1978 · 13,306 citations
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3[59] Glutathione reductase1985 · 2,986 citations
4Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase1974 · 10,277 citations
5Rheumatoid Arthritis: Clinical Features and Pathogenetic Mechanisms1986 · 72 citations

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