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Abstract We show that the mean curvature flow of generic closed surfaces in R^3 R 3 avoids asymptotically conical and non-spherical compact singularities. We also show that the mean curvature flow of generic closed low-entropy hypersurfaces in R^4 R 4 is smooth until it disappears in a round point. The main technical ingredient is a long-time existence and uniqueness result for ancient mean curvature flows that lie on one side of asymptotically conical or compact shrinking solitons.
Chodosh et al. (Tue,) studied this question.