July 1, 1999

Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction

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Abstract

We conclude that caspase-3-mediated apoptosis causes extensive lymphocyte apoptosis in sepsis and may contribute to the impaired immune response that characterizes the disorder.

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Hotchkiss et al. (Thu,) studied this question.

synapsesocial.com/papers/69d8396e8c03fbaff8bee344 https://doi.org/https://doi.org/10.1097/00003246-199907000-00002

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1Importance of apoptosis in the histopathology of drug related lesions in the large intestine.1993 · 205 citations
2Resolution of acute inflammation and the role of apoptosis in the tissue fate of granulocytes1992 · 332 citations
3Delayed Hypersensitivity1977 · 485 citations
4Sir Isaac Newton, sepsis, SIRS, and CARS1996 · 991 citations
5The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee1995 · 2,100 citations

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