Pediatric tracheostomy-associated respiratory infections: an evolving paradigm

Key Points

• This research aims to understand how the airway microbiome affects respiratory infections related to tracheostomy in children.
• Review of current advancements in TRAIN pathobiology
• Assessment of airway microbiome during infections and wellness
• Recommendation for antibiotic clinical trials for optimal treatment
• Identified significant changes in airway microbiome during infections
• Suggested a link between microbiome and host inflammation
• Highlighted the need for clinical trials to improve treatment strategies