Role of Advanced Glycation End Product in the Pathogenesis of Diabetic Retinopathy

Key Points

• The study investigates the relationship between advanced glycation end products and the development of diabetic retinopathy in patients with Type 2 Diabetes Mellitus.
• Comparison of serum AGE levels among patients with and without diabetic retinopathy.
• Analysis of inflammation markers, insulin resistance, and angiogenesis factors.
• Diabetic retinopathy patients have significantly higher serum AGE levels.
• Elevated AGE levels correlate with increased inflammation and insulin resistance.
• AGE contributes to the development of angiogenesis factors linked to diabetic retinopathy.