What question did this study set out to answer?

The aim is to describe the characteristics of diffuse dermal immunoglobulin deposition in patients with monoclonal gammopathy.

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April 10, 2026

Diffuse Dermal Immunoglobulin Deposition and Monoclonal Gammopathy

Key Points

The aim is to describe the characteristics of diffuse dermal immunoglobulin deposition in patients with monoclonal gammopathy.
Conducted a series of clinical evaluations
Used direct immunofluorescence to identify immunoglobulin deposition
Focused on dermatological manifestations in patients
Identified multiple cases with characteristic diffuse dermal immunoglobulin presence
Observed a correlation with monoclonal gammopathy
Highlighted the importance of immunofluorescence in diagnosis

Abstract

This case series describes patients with diffuse dermal immunoglobulin deposition identified using direct immunofluorescence.

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Authors

Mazdak A. Khalighi

University of Utah

Jeremy P. Snook

University of Utah

Margaret Cocks

University of Utah

Journals

JAMA Dermatology

Actions

Institutions

University of Utah

References and Citations

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Cite this study

Khalighi et al. (Wed,) studied this question.

synapsesocial.com/papers/69d8968f6c1944d70ce08114 — DOI: https://doi.org/10.1001/jamadermatol.2026.0516

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Correlation Between Dermal Interstitial Immunoglobulin G and Hypergammaglobulinemia· 1991 · 3 citations
Macroglobulinemia Cutis· 1978 · 29 citations
Light Chain Podocytopathy Mimicking Recurrent Focal Segmental Glomerulosclerosis· 2016 · 10 citations
A Case of Acquired Autoimmune Bullous Disease Associated with IgM Macroglobulinaemia· 1999 · 28 citations
Cutaneous macroglobulinosis: a case series· 2012 · 37 citations

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Correlation Between Dermal Interstitial Immunoglobulin G and Hypergammaglobulinemia· 1991 · 3 citations
Macroglobulinemia Cutis· 1978 · 29 citations
Light Chain Podocytopathy Mimicking Recurrent Focal Segmental Glomerulosclerosis· 2016 · 10 citations
A Case of Acquired Autoimmune Bullous Disease Associated with IgM Macroglobulinaemia· 1999 · 28 citations
Cutaneous macroglobulinosis: a case series· 2012 · 37 citations

Diffuse Dermal Immunoglobulin Deposition and Monoclonal Gammopathy

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Also consider