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Type 1 diabetes immunotherapy using polyclonal regulatory T cells | Synapse

November 25, 2015

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Immuntherapie bei Typ-1-Diabetes mit polyklonalen regulatorischen T-Zellen

Jeffrey A. BluestoneNorthwestern University JBJane H. BucknerVirginia Mason Medical Center MFMark FitchUniversity of California, Berkeley

Key Points

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Abstract

Autologe regulatorische T-Zellen können vermehrt werden und werden bei Patienten mit neu aufgetretenem Typ-1-Diabetes gut toleriert.

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Bluestone et al. (Wed,) untersuchten diese Frage.

synapsesocial.com/papers/69d8a20c183921ebcaae3041 https://doi.org/https://doi.org/10.1126/scitranslmed.aad4134

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3Peripheral CD4+CD8+ T cells are differentiated effector memory cells with antiviral functions2004 · 264 citations
4Measurement of cell proliferation by labeling of DNA with stable isotope-labeled glucose: Studies <i>in vitro</i> , in animals, and in humans1998 · 194 citations
5Glycaemic control of Type 1 diabetes in clinical practice early in the 21st century: an international comparison2014 · 348 citations