January 27, 2015Open Access
Hyperlipidemia in Early Adulthood Increases Long-Term Risk of Coronary Heart Disease
Structured PICO
Does cumulative exposure to hyperlipidemia in young adulthood increase the long-term risk of coronary heart disease?
P
Population
Young adults
I
Intervention
Cumulative exposure to hyperlipidemia (elevations in non-high-density lipoprotein cholesterol)
O
Outcome
Coronary Heart Disease (CHD)hard clinical
Prolonged exposure to even moderate elevations in non-HDL cholesterol in young adulthood increases future CHD risk, suggesting a potential benefit for earlier aggressive primary prevention.
Abstract
Cumulative exposure to hyperlipidemia in young adulthood increases the subsequent risk of CHD in a dose-dependent fashion. Adults with prolonged exposure to even moderate elevations in non-high-density lipoprotein cholesterol have elevated risk for future CHD and may benefit from more aggressive primary prevention.
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Authors
A
Ann Marie Navar‐Boggan
Boston University
Eric D. Peterson
The University of Texas Southwestern Medical Center
R
Ralph B. D’Agostino
Wake Forest University
Journals
Circulation
Actions
Institutions
Boston University
References and Citations
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