July 1, 2021Open Access

Prosthesis-Patient Mismatch After Aortic Valve Replacement in the PARTNER 2 Trial and Registry

Structured PICO

Does severe predicted prosthesis-patient mismatch affect mortality and rehospitalization after SAVR or TAVR?

Population

Patients undergoing surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement (TAVR) in the PARTNER 2 Trial and Registry

Intervention

Assessment of prosthesis-patient mismatch (PPM) using measured versus predicted effective orifice area index (EOAi)

Outcome

Incidence of PPM, all-cause death, and rehospitalizationhard clinical

Severe predicted prosthesis-patient mismatch is rare but significantly increases the risk of death and rehospitalization after SAVR, while it is absent after TAVR.

Abstract

EOAi measured by echocardiography results in a higher incidence of PPM following SAVR or TAVR than PPM based on predicted EOAi. Severe PPMP is rare (<1.5%), but is associated with increased all-cause death and rehospitalization after SAVR, whereas it is absent following TAVR.

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