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Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock | Synapse

November 8, 2001Open Access

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Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

EREmanuel P. RiversUniversity of North Carolina at Chapel Hill BNBryant NguyenLoma Linda University SHSuzanne HavstadBoston University

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Abstract

Early goal-directed therapy provides significant benefits with respect to outcome in patients with severe sepsis and septic shock.

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Rivers et al. (Thu,) studied this question.

synapsesocial.com/papers/69daa19a387cf706986870e7 https://doi.org/https://doi.org/10.1056/nejmoa010307

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1APACHE II-A Severity of Disease Classification System1986 · 13,418 citations
2Critical Assessment of Use of Central Venous Oxygen Saturation as a Mirror of Mixed Venous Oxygen in Severely Ill Cardiac Patients1969 · 231 citations
3Multiple organ failure syndrome in the 1990s. Systemic inflammatory response and organ dysfunction1994 · 112 citations
4World Medical Association Declaration of Helsinki2000 · 2,357 citations
5Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care2001 · 8,613 citations