February 27, 2007Open Access

AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides

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Abstract

By identifying aggregation-prone segments in proteins, AGGRESCAN http://bioinf.uab.es/aggrescan/ shall facilitate (i) the identification of possible therapeutic targets for anti-depositional strategies in conformational diseases and (ii) the anticipation of aggregation phenomena during storage or recombinant production of bioactive polypeptides or polypeptide sets.

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Conchillo‐Solé et al. (Tue,) studied this question.

synapsesocial.com/papers/69daa9b5387cf70698687485 https://doi.org/https://doi.org/10.1186/1471-2105-8-65

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