Hepatic metabolic burden and all-cause mortality across glucose metabolism statuses in a cardiovascular-kidney-metabolic syndrome population: insights from the National Health and Nutrition Examination Survey (NHANES)

Key Points

• The study aims to examine the relationship between hepatic metabolic burden and all-cause mortality across different glucose metabolism statuses in a cardiovascular-kidney-metabolic syndrome population.
• Analyzed data from the National Health and Nutrition Examination Survey (NHANES)
• Assessed FLI (Fatty Liver Index) in relation to all-cause mortality
• Grouped individuals by glycemic status: diabetes, prediabetes, and normoglycemia
• Elevated FLI associated with increased all-cause mortality specifically in individuals with diabetes
• Demonstrated J-shaped association between FLI and mortality in the diabetic group
• No significant association noted between FLI and mortality in normoglycemia or prediabetes groups