AIM: To assess the efficacy and safety of combining laparoscopic suspension with vaginal wall repair for treating Pelvic Organ Prolapse (POP). METHODS: Clinical data from 112 patients with POP admitted to Taishun County People's Hospital between January 2022 and October 2024 were collected and analyzed retrospectively. Based on the surgical method, the subjects were categorized into two groups: 52 patients treated with conventional vaginal wall repair were assigned to the control group, and 60 patients treated with vaginal wall repair combined with laparoscopic suspension were assigned to the study group. General characteristics, perioperative indicators, pelvic floor function, postoperative complications, and quality of life were compared between the two groups. The pelvic floor function was assessed using the Colorectal-Anal Distress Inventory-8 (CRADI-8), Pelvic Organ Prolapse Distress Inventory-6 (POPDI-6), and Urogenital Distress Inventory-6 (UDI-6), whereas the quality of life was measured using the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire-12 (PISQ-12), Pelvic Floor Distress Inventory-20 (PFDI-20), and Pelvic Floor Impact Questionnaire-7 (PFIQ-7). RESULTS: Baseline characteristics were comparable between the two groups (p > 0.05). The study group, however, experienced longer surgery, increased intraoperative blood loss, and extended catheterization compared with the control group, while length of hospital stay and postoperative residual urine volume showed no significant differences (p > 0.05). At three months postoperatively, patients in the study group showed significantly improved scores in CRADI-8, POPDI-6, and UDI-6 compared with the control group (p 0.05). At 12 months postoperatively, the study group had higher PISQ-12 scores and lower PFDI-20 and PFIQ-7 scores compared with the control group (p < 0.001), suggesting more significant improvements in sexual function and quality of life. CONCLUSIONS: Compared with vaginal wall repair alone, the combined approach of laparoscopic suspension and vaginal wall repair improves postoperative pelvic floor function and quality-of-life outcomes without increasing the risk of complications, supporting its role as a valuable surgical option for selected patients with POP.
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